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Vol. 50, Issue 2, 265-270, June 1998
MRC Brain Metabolism Unit (A.J.H) Royal Edinburgh Hospital,
Edinburgh, Scotland;
US-Japan Biomedical Research Laboratories (A.A.),
Tulane University Medical Center, Belle Chasse, Louisiana;
Department
of Clinical Biochemistry (I.G.), Sackler School of Medicine, Tel Aviv
University, Ramat Aviv, Israel;
CNRS UPR 9023 (L.J.), CCIPE, F-34094
Montpellier, France;
INSERM U 410 (M.L.), Faculté de
Médecine Xavier Bichat, Paris, France;
CURE:VA/UCAL DDRC
(J.R.P.), West Los Angeles VA Medical Center, University of California,
Los Angeles, California;
Life Science Resources (S.R.R.), Abberley
House, Great Shelford, Cambridge, England;
Laboratoire de Chimie
Biologique et de la Nutrition (P.R.) Université Libre de
Bruxelles, Bruxelles, Belgium;
School of Medicine (S.I.S.), State
University of New York at Stony Brook, Stony Brook, New York;
Department of Medicine (S.P.S.), Division of Allergy and Immunology,
University of California San Francisco, San Francisco, California;
Digestive Diseases Branch (S.A.W.), NIDDK, National Institutes of
Health, Bethesda, Maryland;
Department of Psychiatry and Mental
Retardation Research Center (J.A.W.), University of California Los
Angeles, Los Angeles, California
I. Introduction
II. The VPAC1 Receptor
III. The VPAC2 Receptor
IV. The PAC1 Receptor
V. Proposed Nomenclature
VI. Unresolved Issues and Conclusions
Acknowledgments
References
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
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|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
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|
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