Pharmacological Reviews Get Tables of Contents delivered automatically
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     



0031-6997/03/5504-597-606$7.00
Pharmacol Rev 55:597-606, 2003

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Neubig, R. R.
Right arrow Articles by Christopoulos, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Neubig, R. R.
Right arrow Articles by Christopoulos, A.

International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on Terms and Symbols in Quantitative Pharmacology

Richard R. Neubig, Michael Spedding, Terry Kenakin and Arthur Christopoulos

Department of Pharmacology, University of Michigan, Ann Arbor, Michigan (R.R.N.); Institute de Recherches Internationales Servier, Neuilly sur Seine, France (M.S.); Systems Research, GlaxoSmithKline Research and Development, Research Triangle Park, North Carolina (T.K.); and Department of Pharmacology, University of Melbourne, Parkville, Australia (A.C.)

Abstract
I. Introduction
II. Working Definition of a Receptor
III. Use of Drugs in Definition of Receptors or of Signaling Pathways
    A. The Expression of Amount of Drug: Concentration and Dose
    B. General Terms Used to Describe Drug Action
    C. Experimental Measures of Drug Action
    D. Terms and Procedures Used in the Analysis of Drug Action
IV. Appendix
    A. Microscopic and Macroscopic Equilibrium Constants
    B. Schild Equation and Plot—Further Detail
    C. The Relationship between the Hill and Logistic Equation
The recommendations that follow have been updated from the proposals of a Technical Subcommittee set up by the International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification (Jenkinson DH, Barnard EA, Hoyer D, Humphrey PPA, Leff P, and Shankley NP (1995) International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. IX. Recommendations on terms and symbols in quantitative pharmacology. Pharmacol Rev 47:255–266).


Address correspondence to: Richard R. Neubig, Department of Pharmacology, 1301 MSRB III/Box 0632, University of Michigan, Ann Arbor, MI 48109-0632. E-mail: RNeubig{at}umich.edu







HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
 Molecular Interventions Drug Metabolism and Disposition
Copyright © 2003 by the American Society for Pharmacology and Experimental Therapeutics