During proofreading of the above article [Zheng CJ, Han LY, Yap CW, Ji ZL, Cao ZW, and Chen YZ (2006) Pharmacol Rev 58:259-279], the authors entered the wrong text data for the percentages of targets and the numbers of similarity proteins, participating pathways, and affiliated tissues into the section "A. 'Rules' for Guiding the Search for Druggable Proteins." The corrected data, listed in bold, are reported below.

On page 275, under the third bullet point, "<6 human similarity proteins" should be replaced by "<15 human similarity proteins"; "51% of the successful targets" should be replaced by "78% of the successful targets"; and "<6 human similarity proteins" should be replaced by "<15 human similarity proteins."

In the first and second sentences under the fourth bullet point, "no more than two pathways" should be replaced by "no more than three pathways," and "(76% of the successful targets with pathway information are associated with no more than two pathways)" should be replaced by "(87% of the successful targets with pathway information are associated with no more than three pathways)," respectively.

In the first sentence under the fifth bullet point, "no more than two tissues in humans" should be replaced by "no more than five tissues in humans."

On pages 275 and 276, again under the fifth bullet point, "(53% of the successful targets with tissue distribution information are distributed in no more than two tissues)" should be replaced by "(79% of the successful targets with tissue distribution information are distributed in no more than five tissues)."

The online version of this article will be corrected in departure from print.

The authors regret these errors and apologize for any confusion they may have caused.