Review ArticleReview Article
Regulation of G Protein-Coupled Receptor Function by Na+/H+ Exchange Regulatory Factors
Juan A. Ardura and Peter A. Friedman
Paul A. Insel, ASSOCIATE EDITOR
Pharmacological Reviews December 2011, 63 (4) 882-900; DOI: https://doi.org/10.1124/pr.110.004176
Juan A. Ardura
Laboratory for G Protein-Coupled Receptor Biology, Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
Peter A. Friedman
Laboratory for G Protein-Coupled Receptor Biology, Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
Paul A. Insel
Laboratory for G Protein-Coupled Receptor Biology, Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
Roles: ASSOCIATE EDITOR
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Review ArticleReview Article
NHERF EFFECTS ON GPCR FUNCTION
Juan A. Ardura and Peter A. Friedman
Pharmacological Reviews December 1, 2011, 63 (4) 882-900; DOI: https://doi.org/10.1124/pr.110.004176
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- Article
- Abstract
- I. Introduction: Historical Background and Discovery
- II. Structure and Structural Determinants of Na+/H+ Exchange Regulatory Factor Proteins
- III. Tissue, Cell, and Subcellular Localization
- IV. G Protein-Coupled Receptor Partners and Effects of Na+/H+ Exchange Regulatory Factor-1 on Trafficking and Signaling
- V. Hormonal Regulation of Na+/H+ Exchange Regulatory Factor-1 Expression
- VI. Biological Actions of Na+/H+ Exchange Regulatory Factors
- VII. Post-Translational Modifications
- VIII. Na+/H+ Exchange Regulatory Factor Mutations and Polymorphisms
- IX. Conclusions and Future Directions
- Acknowledgments
- Authorship Contributions
- Footnotes
- References
- Figures & Data
- Info & Metrics
- eLetters
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