Review ArticleReview Article
Cytokines as Therapeutic Targets in Rheumatoid Arthritis and Other Inflammatory Diseases
Stefan Siebert, Alexander Tsoukas, Jamie Robertson and Iain McInnes
Rhian M. Touyz, ASSOCIATE EDITOR
Pharmacological Reviews April 2015, 67 (2) 280-309; DOI: https://doi.org/10.1124/pr.114.009639
Stefan Siebert
Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom (S.S., J.R., I.M.); and Division of Rheumatology, McGill University Health Centre, Montreal, Quebec, Canada (A.T.)
Alexander Tsoukas
Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom (S.S., J.R., I.M.); and Division of Rheumatology, McGill University Health Centre, Montreal, Quebec, Canada (A.T.)
Jamie Robertson
Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom (S.S., J.R., I.M.); and Division of Rheumatology, McGill University Health Centre, Montreal, Quebec, Canada (A.T.)
Iain McInnes
Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom (S.S., J.R., I.M.); and Division of Rheumatology, McGill University Health Centre, Montreal, Quebec, Canada (A.T.)
Rhian M. Touyz
Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom (S.S., J.R., I.M.); and Division of Rheumatology, McGill University Health Centre, Montreal, Quebec, Canada (A.T.)
Roles: ASSOCIATE EDITOR
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In this issue
Review ArticleReview Article
Cytokines as Therapeutic Targets in Inflammatory Diseases
Stefan Siebert, Alexander Tsoukas, Jamie Robertson and Iain McInnes
Pharmacological Reviews April 1, 2015, 67 (2) 280-309; DOI: https://doi.org/10.1124/pr.114.009639
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- Article
- Abstract
- I. Introduction
- II. The Experience with Current Licensed Cytokine Targets in Rheumatoid Arthritis
- III. Currently Licensed Anticytokine Therapies in Other Chronic Inflammatory Conditions
- IV. Newer Signals and Therapeutic Targets
- V. Lessons from Failed Cytokine Targets in Rheumatoid Arthritis
- VI. Novel Approaches: Small Molecules
- VII. Conclusion
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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