Review ArticleReview Article
Drug Transporters and Na+/H+ Exchange Regulatory Factor PSD-95/Drosophila Discs Large/ZO-1 Proteins
Dustin R. Walsh, Thomas D. Nolin and Peter A. Friedman
Paul A. Insel, ASSOCIATE EDITOR
Pharmacological Reviews July 2015, 67 (3) 656-680; DOI: https://doi.org/10.1124/pr.115.010728
Dustin R. Walsh
Laboratory for G Protein–Coupled Receptor Biology, Department of Pharmacology and Chemical Biology, and Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania (P.A.F.); and Center for Clinical Pharmaceutical Sciences, Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania (D.R.W., T.D.N.)
Thomas D. Nolin
Laboratory for G Protein–Coupled Receptor Biology, Department of Pharmacology and Chemical Biology, and Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania (P.A.F.); and Center for Clinical Pharmaceutical Sciences, Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania (D.R.W., T.D.N.)
Peter A. Friedman
Laboratory for G Protein–Coupled Receptor Biology, Department of Pharmacology and Chemical Biology, and Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania (P.A.F.); and Center for Clinical Pharmaceutical Sciences, Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania (D.R.W., T.D.N.)
Paul A. Insel
Laboratory for G Protein–Coupled Receptor Biology, Department of Pharmacology and Chemical Biology, and Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania (P.A.F.); and Center for Clinical Pharmaceutical Sciences, Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania (D.R.W., T.D.N.)
Roles: ASSOCIATE EDITOR
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In this issue
Review ArticleReview Article
Drug Transporters and NHERF PDZ Proteins
Dustin R. Walsh, Thomas D. Nolin and Peter A. Friedman
Pharmacological Reviews July 1, 2015, 67 (3) 656-680; DOI: https://doi.org/10.1124/pr.115.010728
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- Article
- Abstract
- I. Introduction
- II. Drug Transporter Structure, Function, and Tissue Location
- III. Tissue and Cellular Localization of PSD-95/Drosophila Discs Large/ZO-1 Proteins
- IV. Role of PSD-95/Drosophila Discs Large/ZO-1 Proteins in Regulation of Cell Membrane Abundance, Localization, and Function of Drug Transporters
- V. PSD-95/Drosophila Discs Large/ZO-1 Proteins and Drug Action in Disease States
- VI. Conclusions and Future Directions
- Acknowledgments
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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