Review ArticleReview Article
Biomarkers for In Vivo Assessment of Transporter Function
Fabian Müller, Ashish Sharma, Jörg König and Martin F. Fromm
Martin C. Michel, ASSOCIATE EDITOR
Pharmacological Reviews April 2018, 70 (2) 246-277; DOI: https://doi.org/10.1124/pr.116.013326
Fabian Müller
Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (F.M., J.K., M.F.F.); and Department of Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach a.d. Riß, Germany (F.M., A.S.)
Ashish Sharma
Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (F.M., J.K., M.F.F.); and Department of Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach a.d. Riß, Germany (F.M., A.S.)
Jörg König
Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (F.M., J.K., M.F.F.); and Department of Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach a.d. Riß, Germany (F.M., A.S.)
Martin F. Fromm
Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (F.M., J.K., M.F.F.); and Department of Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach a.d. Riß, Germany (F.M., A.S.)
Martin C. Michel
Roles: ASSOCIATE EDITOR
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In this issue
Review ArticleReview Article
Biomarkers for Assessment of Transporter Function
Fabian Müller, Ashish Sharma, Jörg König and Martin F. Fromm
Pharmacological Reviews April 1, 2018, 70 (2) 246-277; DOI: https://doi.org/10.1124/pr.116.013326
Jump to section
- Article
- Abstract
- I. Introduction
- II. Drug Transporters
- III. Biomarkers for Transporter Function
- IV. Suggested Factors To Be Considered for Biomarkers of Transporter Function
- V. Alternatives and Supplemental Approaches to Classic Drug–Drug Interaction Studies
- VI. Conclusions and Outlook
- Acknowledgments
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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