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Effectiveness of yohimbine in the treatment of erectile disorder: Four meta-analytic integrations

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Abstract

The results of four independent yet convergent meta-analyses to examine the efficacy of yohimbine in the treatment of erectile disorder are reported. These meta-analyses integrated data from (i) controlled clinical trials of yohimbine (when used alone), (ii) uncontrolled trials examining yohimbine (alone), (iii) controlled trials of yohimbine when used in combination with other drugs, and (iv) uncontrolled trials of yohimbine plus other drugs. Results document a consistent tendency for yohimbine, and for other medications containing yohimbine, to enhance erectile functioning relative to placebo. We also identify methodological and reporting difficulties that characterize much of the literature.

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Supported in part by grants from the National Institute of Mental Health and Palisades Pharmaceuticals to Michael P. Carey.

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Carey, M.P., Johnson, B.T. Effectiveness of yohimbine in the treatment of erectile disorder: Four meta-analytic integrations. Arch Sex Behav 25, 341–360 (1996). https://doi.org/10.1007/BF02437578

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