RT Journal Article SR Electronic T1 Procedures available to examine the immunotoxicity of chemicals and drugs. JF Pharmacological Reviews JO Pharmacol Rev FD American Society for Pharmacology and Experimental Therapeutics SP 137 OP 148 VO 34 IS 1 A1 J H Dean A1 M I Luster A1 G A Boorman A1 L D Lauer YR 1982 UL http://pharmrev.aspetjournals.org/content/34/1/137.abstract AB The discipline of immunology should provide toxicology with sensitive models to assess toxicity as well as provide better safety assessment. More information on correlations between immune function and host resistance changes and a more standardized panel of methods for immunotoxicity screening will add further credence to the already impressive immunotoxicology data base. Research efforts are needed to evaluate newer in vitro methods with microsome activation systems to screen chemicals for immunotoxicity, to evaluate chemicals for induction of hypersensitization or allergy, and to better determine whether there are chemical structure activity relationships for chemically induced immunotoxicity. The studies described here represent preliminary examples of these approaches.