PT - JOURNAL ARTICLE AU - Charles R. Schuster TI - Drugs as Reinforcers in Monkey and Man DP - 1975 Dec 01 TA - Pharmacological Reviews PG - 511--521 VI - 27 IP - 4 4099 - http://pharmrev.aspetjournals.org/content/27/4/511.short 4100 - http://pharmrev.aspetjournals.org/content/27/4/511.full SO - Pharmacol Rev1975 Dec 01; 27 AB - I have presented data to illustrate and evaluate the use of animal experiments on behavior maintained by drug injection as an animal model of human drug abuse. I believe, the data justify the cautious application of such an animal model for predicting the abuse potential of a new drug, for evaluating new forms of treatment, and finally, for investigating biological and environmental variables controlling drug taking behavior. However, there are a variety of assumptions whenever we extrapolate conclusions from laboratory studies to man in his natural environment. 1971, by The Williams & Wilkins Co.