RT Journal Article
SR Electronic
T1 International Union of Pharmacology. XLVIII. Nomenclature and Structure-Function Relationships of Voltage-Gated Calcium Channels
JF Pharmacological Reviews
JO Pharmacol Rev
FD American Society for Pharmacology and Experimental Therapeutics
SP 411
OP 425
DO 10.1124/pr.57.4.5
VO 57
IS 4
A1 William A. Catterall
A1 Edward Perez-Reyes
A1 Terrance P. Snutch
A1 Joerg Striessnig
YR 2005
UL http://pharmrev.aspetjournals.org/content/57/4/411.abstract
AB The family of voltage-gated calcium channels serves as the key transducers of cell surface membrane potential changes into local intracellular calcium transients that initiate many different physiological events. There are 10 members of the voltage-gated calcium channel family that have been characterized in mammals, and they serve distinct roles in cellular signal transduction. This article presents the molecular relationships and physiological functions of these calcium channel proteins and provides comprehensive information on their molecular, genetic, physiological, and pharmacological properties.