TY - JOUR T1 - International Union of Pharmacology. LX. Retinoic Acid Receptors JF - Pharmacological Reviews JO - Pharmacol Rev SP - 712 LP - 725 DO - 10.1124/pr.58.4.4 VL - 58 IS - 4 AU - Pierre Germain AU - Pierre Chambon AU - Gregor Eichele AU - Ronald M. Evans AU - Mitchell A. Lazar AU - Mark Leid AU - Angel R. De Lera AU - Reuben Lotan AU - David J. Mangelsdorf AU - Hinrich Gronemeyer Y1 - 2006/12/01 UR - http://pharmrev.aspetjournals.org/content/58/4/712.abstract N2 - Retinoid is a term for compounds that bind to and activate retinoic acid receptors (RARα, RARβ, and RARγ), members of the nuclear hormone receptor superfamily. The most important endogenous retinoid is all-trans-retinoic acid. Retinoids regulate a wide variety of essential biological processes, such as vertebrate embryonic morphogenesis and organogenesis, cell growth arrest, differentiation and apoptosis, and homeostasis, as well as their disorders. This review summarizes the considerable amount of knowledge generated on these receptors. ER -