RT Journal Article SR Electronic T1 International Union of Pharmacology. LXIX. Status of the Calcitonin Gene-Related Peptide Subtype 2 Receptor JF Pharmacological Reviews JO Pharmacol Rev FD American Society for Pharmacology and Experimental Therapeutics SP 143 OP 145 DO 10.1124/pr.108.00372 VO 60 IS 2 A1 Debbie L. Hay A1 David R. Poyner A1 Remi Quirion YR 2008 UL http://pharmrev.aspetjournals.org/content/60/2/143.abstract AB Historically, calcitonin gene-related peptide (CGRP) receptors have been divided into two classes, CGRP1 and CGRP2. After the cloning of calcitonin receptor-like receptor (CLR) and receptor activity-modifying proteins (RAMPs), it became clear that the CGRP1 receptor was a complex between CLR and RAMP1. It is now apparent that the CGRP2 receptor phenotype is the result of CGRP acting at receptors for amylin and adrenomedullin. Accordingly, the term “CGRP2” receptor should no longer be used, and the “CGRP1” receptor should be known as the “CGRP” receptor.