Primary G protein coupling for prostanoid receptors
| Prostanoid Receptor Subtype | Prostanoid Molecular Evolution Cluster | G Protein | Second Messenger |
|---|---|---|---|
| DP1 | 1 | Gs | ↑ cAMP |
| EP1 | 2 | ↑ [Ca2+]i | |
| EP2 | 1 | Gs | ↑ cAMP |
| EP3 | 3 | Gi | ↓ cAMP |
| EP4 | 1 | Gs | ↑ cAMP |
| FP | 2 | Gq | ↑ [Ca2+]i PI turnover |
| IP | 1 | Gs | ↑ cAMP |
| TP | 2 | Gq | ↑ [Ca2+]i PI turnover |