Table 3

Drug binding sites in red blood cells

CompoundBinding siteReference
Chlorpromazine Bickel (1975)
Codeine Mohammed et al. (1993)
ImipraminePlasma membrane Bickel (1975)
Mefloquine San George et al. (1984)
Pyrimethamine Rudy and Poynor (1990)
DraflazineNucleoside transporter Snoek et al. (1996)
Acetazolamide Wallace and Riegelman (1977)
Chlorthalidone Collste et al. (1976)
DorzolamideCarbonic anhydrase Biollaz et al. (1995)
Methazolamide Bayne et al. (1981)
MK-927 Lin et al. (1992)
Cyclosporin ACyclophilin Agarwal et al. (1986)
TacrolimusTacrolimus binding protein Hooks (1994)
Aminophenzone Hilzenbecher (1972)
Barbituates Hilzenbecher (1972)
Chlordiazepoxide Hilzenbecher (1972)
Digoxin and derivatives Hinderling (1984a)
Imipramine and derivatives Hilzenbecher (1972)
Mefloquine San George et al. (1984)
Nitrofurantoin Hilzenbecher (1972)
Oxyphenbutazone Hilzenbecher (1972)
PhenothiazinesHemoglobin Hilzenbecher (1972)
Phenylbutazone Hilzenbecher (1972)
Phenytoin Hilzenbecher (1972)
Proquazone Roos and Hinderling (1981)
Pyrimethamine Rudy and Poynor (1990)
Salicylic acid and congeners Hilzenbecher (1972)
Sulfinpyrazone Hilzenbecher (1972)
Sulfonamides Berneis and Boguth (1976)