Table 3

Specific actions of individual integrins

Specific integrinBiological effectReference
β1c (alternatively spliced β subunit)Growth inhibition(Fornaro et al., 1995)
β6Growth promotion(Dixit et al., 1996)
αvβ3Control of apoptosis in endothelial cells(Brooks et al., 1994)
α6β4Growth control in epithelial cells(Mainiero et al., 1997)
α5β1Control of apoptosis(Zhang et al., 1995c)
α2β1Growth control in smooth muscle cells(Koyamaet al., 1996a)
α6β1Differentiation of skeletal muscle cells(Sastry et al., 1996)
αv integrinsIncrease cell calcium(Schwartz and Denninghoff, 1994)