Regulation of gene expression by cell adhesion receptors
| Receptor Involved | Gene Regulated | Cell Type | Reference |
|---|---|---|---|
| β1 integrins | IE genes (cytokines TFs) | Human monocytes | (Yurochko et al., 1992) |
| β1 integrins | Tissue factor | Human monocytes | (Fan et al., 1995) |
| β1 integrins (other integrins?) | Milk genes | Mouse breast cells | (Streuli et al., 1991) |
| β1 integrins | Muscle-specific genes | Quail myoblasts | (Sastry et al., 1996) |
| β1 integrins | Metalloproteases | Synovial fibroblasts | (Werb et al., 1989) |
| β1 integrins | Cytokines | Chondrocytes | (Yonezawa et al., 1996) |
| β2 integrins | E-selectin | Endothelial cells | (Nobleet al., 1996) |
| αvβ3 | Metalloproteases | Melanoma | (Seftor et al., 1992) |
| αvβ3 | p53 | Endothelial | (Strombladet al., 1996) |
| α5β1 | IE genes | Colon carcinoma cells | (Varner et al., 1995) |
| α5β1 | Bcl-2 | CHO cells | (Zhang et al., 1995c) |
| Integrins | IL-2 | T cells | (Udagwa et al., 1996) |
| Matrix (integrins?) | Integrins | Breast epithelia | (Delcommenne and Streuli, 1995) |
| Matrix (integrins?) | Liver specific | Hepatocytes | (DiPersio et al., 1991; Liuet al., 1991) |
| CEA (an Ig-CAM) | NCAM, MUC18 | Melanoma | (Grimm and Johnson, 1995) |
| E-cadherin | Syndecan (a proteoglycan) | Mammary tumor cells | (Leppa et al., 1996) |