The catabolism of retinoic acid to polar metabolites
| Enzyme | Locus | Reaction | Binding protein/function |
|---|---|---|---|
| Cytochrome P450-isoenzymes | Microsomal | ||
| P450RAI | Retinoic acid → 4-OH-retinoic acid | CRABP-retinoic acid/substrate | |
| CYP1A1 | Retinoic acid → 4-OH-retinoic acid | CRABP-retinoic acid/substrate | |
| CYP1A2 | |||
| CYP2B4 | |||
| CYP2C3 | |||
| CYP2E1, 2 | |||
| CYP2G2 | |||
| CYP3A |