Table 1
Comparison of type I and type II amiodarone-induced thyrotoxicosis
AIT-I
AIT-II
Underlying abnormality
Yes or no
No
Radioiodine uptake
Normal/increased
Decreased
Pathogenesis
Excess iodide
Destructive
Serum IL-6
Slightly increased
Markedly increased
Therapy
Perchlorate (+MMI)
Corticosteroids