Ion channels |
Inwardly-rectifying K+ channels |
Cardiac KAChchannels1-a
| PTX-sensitive | Stimulation |
Other KGchannels1-b
| PTX-sensitive | Stimulation |
Voltage-dependent Ca2+ channels |
N-type | PTX-sensitive | Inhibition |
L-type | PTX-sensitive | Inhibition |
Enzymes |
Adenylyl cyclase |
Type I | | Inhibition (when activated by GSα) |
Type II | | Stimulation (synergistically with GSα) |
Type IV | | Stimulation (synergistically with GSα) |
Phospholipase C-β1-3 | PTX-insensitive | Stimulation |
Phosphatidylinositol 3-kinase | PTX-sensitive | Stimulation |
G protein-coupled receptor kinase | | Facilitation of membrane translocation |
Phospholipase A2
| PTX-sensitive | Stimulation |
MAP kinase (ras-dependent pathway) | | Stimulation |
Unidentified signal transduction pathway |
Pheromon-induced mating (yeast) | | Stimulation |
Oocytes maturation (starfish) | | Stimulation |