Table 3

Tissue expression of mRNAs for GIRK subunits

	GIRK1	GIRK2	GIRK3	GIRK4
Brain	++^a,b,i	++^c,f,g,i	++^c	+^i,j
Eye	+ⁱ	+ⁱ		+ⁱ
Submaxillary Gland		−^h
Heart
Atrium	++^a,b,i,d	−^c,f,g,h,i	−^c	++^e,i,j,k
Ventricle	±^a,b,d	−^c,g,h	−^c	±^e,kor ++^j
Aorta	+ⁱ	−ⁱ		−^i,j
Thymus		−^g		−ⁱ
Lung	+^b,i or −^d	−^c,f,h,i	−^c	+ⁱ
Liver	±^a,i	−^c,f,h,i	−^c	−^i,j
Spleen	−ⁱ	−^f,h,i		−^i,j
Pancreas		+^f		±^j
Kidney	−^d or +ⁱ	−^c,f,h,i	−^c	−ⁱ or +^j
Stomach	+ⁱ	−ⁱ		−ⁱ
Small Intestine	+ⁱ	−^h,i		−ⁱ
Colon	+ⁱ	−ⁱ		−ⁱ
Adrenal Gland		−^h
Urinary Bladder	+ⁱ	−ⁱ		+ⁱ
Testis	+ⁱ	+^f,h,i		−ⁱ
Ovary		−^h
Uterus	+ⁱ	−^h,i		+ⁱ
Skin	+ⁱ	−ⁱ		−ⁱ
Skeletal Muscle	±^a,b,i	−^c,f,h,i	±^c	+ⁱor −ⁱ

++, strong expression; +, distinct expression; ±, marginal expression; and −, no expression.
References and experimental conditions: ^a Kubo et al., 1993: Northern blot analysis of rat tissues;^b Dascal et al., 1993: Northern, rat;^c Lesage et al., 1994: Northern, mouse;^d Karschin et al., 1994: In situ hybridization, rat; ^e Krapivinski et al., 1995a: Northern, rat;^f Stoffel et al., 1995: Northern, rat;^g Bond et al., 1995: Northern, rat; ^h Bondet al., 1995: RT-PCR, rat; ⁱ Dixon et al., 1995: RT-PCR, rat; ^j Iizuka et al., 1995: Northern, pig; and ^k Spayschus et al., 1996, In situ hybridization, rat.