Table 1

Percentage of homology in 18-kDa PBR subunit gene and affinity of PK 11195 and Ro 5-4864 in various species

	% Homology to Human PBR	Reference	K_i		Reference
	% Homology to Human PBR	Reference	PK 11195	Ro 5-4864	Reference
			nM
Human kidney	100	Riond et al., 1991	4	400	Awad and Gavish, 1991
Bovine kidney	85	Parola et al., 1991	2	4,800	Awad and Gavish, 1987
Mouse kidney	82	Garnier et al., 1994b	1^1-a	1^1-a	Park et al., 1997
Rat kidney	77	Sprengel et al., 1989	2	12	Awad and Gavish, 1987
E. coli	55	Weisinger et al., unpublished data	>10,000	ND	Weisinger et al., unpublished data