Table 2

Selected animal models of pulmonary PMN migration

Airway StimulusCD18 Dependency for Migration
Bacteria and bacterial products
 Gram-negative (LPS; endotoxin)Dependent
 Gram-positive (lipoteichoic acid)Independent
Acid aspiration (hydrochloric acid)Independent
IL-1Dependent
Complement protein C5aPartial dependency
Immune-complex deposition (IgG)Partial dependency