Soluble guanylyl cyclase isoform chromosomal localization and tissue distribution
| Subunit | Chromosome Location1-a | Tissue Distribution |
|---|---|---|
| α1 (α3) | 4q31.3–q33 (Giuili et al., 1993)1-b | Lung (Koesling et al., 1990); cerebellum, cerebrum, heart, kidney, liver, lung, skeletal muscle (Nakane et al., 1990); kidney (Ujiie et al., 1993) |
| α2 | 11q21–q22 (Yu et al., 1996) | Brain, retina (Harteneck et al., 1991); kidney (Ujiie et al., 1993); placenta (Russwurm et al., 1998) |
| β1 (β3) | 4q31.3–q33 (Giuili et al., 1993) | Lung (Koesling et al., 1988); cerebellum, cerebrum, heart, kidney, liver, lung, skeletal muscle (Nakane et al., 1990); kidney (Ujiie et al., 1993); placenta (Russwurm et al., 1998) |
| β2 | 13q14.3 (Behrends et al., 1999) | Kidney, liver (Yuen et al., 1990); kidney (Ujiie et al., 1993) |