Physiological Response | Pathophysiological Response |
---|---|
• Contraction | • ↑ contraction → ↑ peripheral resistance → BP |
• Cell growth | • ↑ growth → ↑ media width → vascular remodeling → ↑ BP |
• Apoptosis | • ↓ apoptosis → ↑ growth → vascular remodeling → ↑ BP |
• Production of collagen, fibronectin, etc. | • ↑ extracellular matrix deposition → vascular remodeling → ↑ BP |
• Inflammatory response | • Atherosclerosis |
• Cell migration | • Vascular remodeling |
• Atherosclerosis |
↑, increase; ↓, decrease; BP, blood pressure.