Distribution of α2-adrenoceptor subtypes in blood vessels
| Species and Vessel | Functional Subtype | Reference |
|---|---|---|
| Prejunctional | ||
| Rat | ||
| Femoral vein | α2D | Paiva et al., 1999 |
| Dog | ||
| Mesenteric artery | α2A | Daniel et al., 1995 |
| Mesenteric vein | α2A | Paiva et al., 1999 |
| Saphenous vein | α2A, α2C | Paiva et al., 1997 |
| Human | ||
| Gastric artery | α2A | Guimarães et al., 1998 |
| Ileocolic artery | α2A | Guimarães et al., 1998 |
| Saphenous vein | α2A | Molderings and Göthert, 1995 |
| Postjunctional | ||
| Mouse | ||
| Tail artery | α2D, α2C | Chotani et al., 2000 |
| Pressor response (anesthetized mouse) | α2B, α2D | Link et al., 1996 |
| Pressor response (pithed mouse) | α2B, α2D | McCafferty et al., 1999 |
| Rat | ||
| Cremaster arterioles | α2D | Leech and Faber, 1996 |
| Cremaster venules | α2D | Leech and Faber, 1996 |
| Pressor response (pithed rat) | α2D, α2B | Gavin and Docherty, unpublished data |
| Dog | ||
| Saphenous vein | α2A | Hicks et al., 1991; MacLennan et al., 1997 |
| Pig | ||
| Common digital artery | α2A | Blayloch and Wilson, 1995 |
| Palmar lateral vein | α2A | Blayloch and Wilson, 1995 |
| Human | ||
| Choriocapillaris (retinal pigmented epithelium) | α2A | Bylund and Chacko, 1999 |
| Saphenous vein | α2C | Gavin et al., 1997 |
1-150 Because α2A and α2D-adrenoceptors are orthologous, this table also shows the species distribution of each ortholog.