α2A/D | α2B | α2C | |
---|---|---|---|
Dog saphenous vein | r = 0.905-150 | r = 0.78 | r = 0.855-150 |
Slope = 0.955-150 | Slope = 0.41 | Slope = 0.895-150 | |
Human gastric artery | r = 0.945-150 | r = 0.66 | r = 0.71 |
Slope = 1.285-150 | Slope = 0.615-150 | Slope = 0.88 | |
Human ileocolic artery | r = 0.965-150 | r = 0.68 | r = 0.57 |
Slope = 1.395-150 | Slope = 0.77 | Slope = 0.88 |
Correlation between pEC30% values of antagonists at prejunctional α2-autoreceptors of the canine saphenous vein (Paiva et al., 1997), and human gastric and iliocolic arteries (Guimarães et al., 1998b) and pK i values at binding sites (HT29 cells, in A; neonatal rat lung, in B; OK cells, in C; and rat submaxillary gland, in D).
↵5-150 p < 0.05.