Table 2

Competition of [Tyr14]OFQ/N binding to the cloned NOP1 receptor in CHO cells

LigandKi values
nM
OFQ/N0.088  ± 0.007
[Tyr14]OFQ/N0.071  ± 0.019
OFQ/N(1–7)>1000
OFQ/N(1–11)55  ± 22
NalBzoH310  ± 75
Morphine>1000
U50,488H>1000
DPDPE>1000
Diprenorphine>1000
  • Data taken from Pan et al., 1996c.