The effects of β2AR stimulation and cAMP-elevating agents on B cell proliferation in vitro
| Effect | Stimulus | References |
|---|---|---|
| ↑4-aProliferation | cAMP | |
| IL-1 and anti-Ig-stimulated B cells | Hoffmann, 1988 | |
| PMA/ionomycin-stimulated B cells | Cohen and Rothstein, 1989 | |
| IL-4 and anti-Ig-stimulated B cells | Vazquez et al., 1991 | |
| β2AR | ||
| LPS-stimulated B cells | Li et al., 1990 | |
| ↓ Proliferation | cAMP | |
| LPS-stimulated nude spleen cells | Diamantstein and Ulmer, 1975 | |
| B cell precursor line | Blomhoff et al., 1987 | |
| IL-4 and anti-Ig-stimulated B cells | Hoffman, 1988 | |
| Anti-Ig-stimulated B cells | Cohen and Rothstein, 1989 | |
| IL-2 and anti-Ig-stimulated B cells | Vazquez et al., 1991 |
↵4-a Abbreviations: ↑, increase; ↓, decrease; β2AR, β2-adrenergic receptor; Ig, immunoglobulin; IL, interleukin; LPS, lipopolysaccharide; NE, norepinephrine; PMA, phorbol ester.