Brief summary of the principal animal models of acute pain
| Thermal | Mechanical | Chemical | Electrical | ||
|---|---|---|---|---|---|
| Long Trains | Single Shocks or Short Trains | ||||
| Phasic pain models | Tail-flick test Paw withdrawal test Hot-plate test | Randall and Selitto | Mechanical stimulation following chemical sensitization (carrageenin, capsaicin, etc.) | Tail Flinch-jump test | Tail Dental pulp Limbs |
| Tonic pain models | Distension of hollow organs | Intradermal injections (formalin test) | |||
| Intraperitoneal injections (writhing test) | |||||