Receptor/Peptide | HUGO gene Name | Accession Number | Human Chromosomal Location |
---|---|---|---|
CT receptor | CALCR | SWMain:P30988 | 7q21.3 |
CL receptor | CALCRL | SWMain:Q16602 | 2q32.1 |
RAMP1 | RAMP1 | SWMain:O60894 | 2q37.3 |
RAMP2 | RAMP2 | SWMain:O60895 | 17q21.2 |
RAMP3 | RAMP3 | SWMain:O60896 | 7p13 |
CT/αCGRP | CALCA | SWMain:P01258 | 11p15.2 |
SWMain::P06881 | |||
βCGRP | CALCB | SWMain:P10092 | 11p15.2 |
AM | ADM | SWMain:P35318 | 11p15.2 |
AMY | IAPP | SWMain:P10997 | 12p12.1 |
HUGO, human genome organization; IAPP, islet amyloid polypeptide.
The CALCA, CALCB, and ADM genes are within a 5-megabase region on chromosome 11p15, with CALCA and CALCB adjacent to each other. This is almost certainly the result of gene duplication.