Gender-associated differences in transport systems in humans
| Compounds | Tissue | Process | Gender Effects | Reference |
|---|---|---|---|---|
| Amantadine | Kidney | Urinary recovery at 48 h | M > F | Wong et al., 1995 |
| Renal clearance/weighta | M > F | Wong et al., 1995 | ||
| Uric acid | Kidney | Postsecretory reabsorption | M > F | Anton et al., 1986 |
| Rifamycin SV | Liver | Normal & Gilbert's patients | M < F | Gentile et al., 1985 |
| MDR1 (Pgp) | Liver | Protein expression | M > F | Schuetz et al., 1995 |
| Glucose | Skeletal muscles | Uptake | M < F | Nuutila et al., 1995 |
| Chylomicron | Splanchnic | Uptake | M > F | Nguyen et al., 1996 |
| Triglyceride | tissues | |||
| Palmitate | Splanchnic | Uptake | M > F | Nguyen et al., 1996 |
↵ a Renal clearance in males was greater than in females following normalization for body weight, body surface area, or body mass index