Table 2

Response to plasma carnitine depletion

Plasma total carnitine concentration2-a
 Pre-dialysis73 μM
 Immediately post-dialysis37 μM
 Net loss of carnitine by patient2-b 0.63 mmol
 Percentage of tissue carnitine pool shifted to extracellular to replenish losses2-b 0.5%
  • 2-a  Data from Guarnieri et al., 1987.

  • 2-b  Based on 70 kg of body weight, 25% body weight as extracellular fluid and tissue carnitine content per kilogram (see Table 1). Assumes no carnitine intake or biosynthesis over dialysis interval.