Most common haplotypes and frequencies (>5%) in several populations
| Nucleotide | −1023 | −709 | −654 | −468 | −406 | −367 | −47 | −20 | 46 | 79 | 252 | 491 | 523 | Ca | A A | As | H-L |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alleles | G/A | C/A | G/A | C/G | C/T | T/C | T/C | T/C | G/A | C/G | G/A | C/T | C/A | ||||
| Location | 5′ | 5′ | 5′ | 5′ | 5′ | 5′ | 5′LC | 5′ | Gly16Arg | Gln27Glu | syn | Thr164Ile | syn | ||||
| Haplotype: | |||||||||||||||||
| 1 | A | C | G | C | C | T | T | T | A | C | G | C | C | 0.7a | 25.0a | 12.5a | 10.0a |
| 2 | A | C | G | G | C | C | C | C | G | G | G | C | C | 48.3 | 6.3 | 10.0 | 26.7 |
| 4 | G | C | A | C | C | T | T | T | A | C | G | C | C | 33.0 | 29.7 | 45.0 | 40.0 |
| 6 | G | C | G | C | C | T | T | T | G | C | A | C | A | 13.2 | 31.3 | 30.0 | 13.3 |
Nucleotide number is based on the first nucleotide of the start codon being + 1. The frequencies are reported for the indicated populations as follows: Ca, Caucasian; A A, African American; As, Asian; H-L, Hispanic-Latino. Alleles, the two nucleotide possibilities at each SNP position. 5′,5′ upstream of the β2AR open reading frame; 5′LC, 5′ leader cistron; Syn, synonymous SNP. Adapted from Drysdale et al., 2000.
↵ a Frequency is shown by percentage.