TABLE 1

The five classes of inducers of CYPs

Inducer Classes/Prototypes Examples of Induced CYPs
Polycyclic aromatic hydrocarbons, TCDD CYP1A1, CYP1A2, CYP1B1
Phenobarbital-type CYP2Bs, CYP2Cs, CYP3As
Rifampicin-, dexamethasone-type CYP3As, CYP2Cs, CYP2Bs
Ethanol, isoniazide CYP2E1
Clofibrate-type CYP4As