Behavioral teratogenicity of perinatal phenytoin and phenobarbital in rats
| Effect | Phenytoin | Phenobarbital |
|---|---|---|
| Spatial learning | ↓ | ↓ |
| Activity | ↑ | ? |
| Motor coordination | ↓ | ↓ |
| Operant learning | NA | ↓ |
| Conditioned avoidance | NE | ↓ |
NA, no information available; NE, no effect.
Adapted from Hansen and Holson (1998).