Historical steps in the characterization of the Na+/Ca2+ exchanger
| Year | |
|---|---|
| 1968 | Description of the exchanger activity in squid axon (Baker et al., 1968) |
| 1988 | Purification of the cardiac exchanger (Philipson and Nicoll, 1988) |
| 1990 | Cloning of NCX1 (Nicoll et al., 1990) |
| 1994–1996 | Cloning of brain specific isoforms NCX2 (Li et al., 1994) and NCX3 (Nicoll et al., 1996) |
| 1997 | NCX isoforms are differentially expressed in several tissues (Quednau et al., 1997) |
| 1999 | Proposal for a new topological model for NCX1 (Nicoll et al., 1999) |