Effective concentrations of tBuBHQ in smooth muscle
| Tissue | Animal Species | Experimental Details (Preparation; Measurement Method; Measured Response) | Effective Concentrations of tBuBHQ | Reference |
|---|---|---|---|---|
| μM | ||||
| Aorta | Pig | Microsomes, F3 microsomal membranes fraction; inorganic phosphate-release assay; Ca2+-ATPase activity | 30-50 | Luo et al., 2000 |
| Aorta | Rabbit | Isolated rings; isometric dynamometry; contractile activity | 30-50 | Luo et al., 2000 |
| Aorta | Rat | Saponin-permeabilized cultured A7r5 cell line; 45Ca2+ cellular loading; Ca2+ fluxes | 50 | Missiaen et al., 1992a |
| Aorta | Rat | Isolated smooth muscle cells; fura-2 cellular loading, fluorometry; [Ca2+]cyt | 20 | Neylon et al., 1992 |
| Aorta | Rat | Isolated endothelium-denuded rings; isometric dynamometry; contractile activity | 50 | Fusi et al., 1998 |
| Aorta | Rat | Isolated endothelium-denuded rings; isometric dynamometry; contractile activity | 10-100 | Shimamoto et al., 1992 |
| Coronary artery | Pig | Isolated smooth muscle cells; fura-2 cellular loading, fluorometry; [Ca2+]cyt | 1 | Weirich et al., 2001 |
| Tail artery | Rat | Isolated smooth muscle cells; whole-cell patch-clamping; ICa(L) | 10-100 | Fusi et al., 2001 |