a | Blood and blood-forming organ diseases | 13 | 2 | | 8 | 1 | 1 | 1 | 2 | 2 | 0 | 0 | 1 | 0 | 2 | 0 | 4 | 2 | 3 | 1 | 1 |
b | Circulatory system diseases | 54 | 9 | 8 | | 11 | 10 | 10 | 24 | 15 | 6 | 7 | 6 | 2 | 6 | 12 | 19 | 6 | 8 | 8 | 2 |
c | Digestive system diseases | 19 | 4 | 1 | 11 | | 5 | 3 | 8 | 9 | 4 | 3 | 5 | 1 | 2 | 5 | 5 | 3 | 6 | 1 | 1 |
d | Genitourinary system diseases | 24 | 0 | 1 | 10 | 5 | | 6 | 11 | 7 | 3 | 6 | 1 | 1 | 2 | 6 | 12 | 1 | 2 | 2 | 3 |
e | Musculoskeletal system and connective tissue diseases | 23 | 4 | 1 | 10 | 3 | 6 | | 10 | 6 | 2 | 2 | 5 | 4 | 6 | 6 | 12 | 1 | 5 | 2 | 3 |
f | Nervous system and sense organ diseases | 56 | 7 | 2 | 24 | 8 | 11 | 10 | | 17 | 4 | 6 | 3 | 2 | 7 | 27 | 13 | 3 | 14 | 7 | 2 |
g | Respiratory system diseases | 35 | 5 | 2 | 15 | 9 | 7 | 6 | 17 | | 5 | 3 | 8 | 2 | 5 | 12 | 10 | 2 | 8 | 4 | 1 |
h | Skin and subcutaneous tissue diseases | 13 | 2 | 0 | 6 | 4 | 3 | 2 | 4 | 5 | | 3 | 3 | 1 | 1 | 2 | 7 | 2 | 2 | 2 | 1 |
i | Endocrine disorders | 21 | 6 | 0 | 7 | 3 | 6 | 2 | 6 | 3 | 3 | | 3 | 0 | 3 | 3 | 8 | 4 | 1 | 1 | 1 |
j | Immunity disorders | 18 | 2 | 1 | 6 | 5 | 1 | 5 | 3 | 8 | 3 | 3 | | 3 | 6 | 2 | 9 | 2 | 3 | 2 | 1 |
k | Infectious and parasitic diseases | 78 | 57 | 0 | 2 | 1 | 1 | 4 | 2 | 2 | 1 | 0 | 3 | | 4 | 1 | 17 | 4 | 1 | 1 | 2 |
l | Inflammation | 15 | 1 | 2 | 6 | 2 | 2 | 6 | 7 | 5 | 1 | 3 | 6 | 4 | | 2 | 8 | 1 | 4 | 1 | 1 |
m | Mental disorders | 46 | 10 | 0 | 12 | 5 | 6 | 6 | 27 | 12 | 2 | 3 | 2 | 1 | 2 | | 5 | 3 | 10 | 2 | 0 |
n | Neoplasms | 78 | 29 | 4 | 19 | 5 | 12 | 12 | 13 | 10 | 7 | 8 | 9 | 17 | 8 | 5 | | 5 | 5 | 6 | 4 |
o | Nutritional and Metabolic diseases | 21 | 5 | 2 | 6 | 3 | 1 | 1 | 3 | 2 | 2 | 4 | 2 | 4 | 1 | 3 | 5 | | 1 | 0 | 0 |
p | Symptoms, signs, and ill-defined conditions | 22 | 2 | 3 | 8 | 6 | 2 | 5 | 14 | 8 | 2 | 1 | 3 | 1 | 4 | 10 | 5 | 1 | | 1 | 2 |
q | Injury and poisoning | 15 | 3 | 1 | 8 | 1 | 2 | 2 | 7 | 4 | 2 | 1 | 2 | 1 | 1 | 2 | 6 | 0 | 1 | | 0 |
r | Congenital anomalies | 4 | 0 | 1 | 2 | 1 | 3 | 3 | 2 | 1 | 1 | 1 | 1 | 2 | 1 | 0 | 4 | 0 | 2 | 0 | |
Total successful therapeutic targets based on disease classes | 555 (duplicate); 268 (distinct) | 148 | Redundancy of therapeutic targets = 120; nonredundancy of therapeutic targets = 148 |