Selective list of the potentially targeted heme proteins by CO
| Name of Protein | Effects of CO or HO Up-Regulation | Reference |
|---|---|---|
| Catalase | Inhibition | Hu and Kincaid (1992) |
| Cyclooxygenase | Inhibition | Alcaraz et al. (2003) |
| Activation | Lee et al. (2001) | |
| Cytochrome c | Binding | Bhuyan and Kumar (2002) |
| Cytochrome P450 | Inhibition | Estabrook et al. (1980) |
| Cytochrome c oxidase | Inhibition | Wohlrab and Ogunmola (1971) |
| Guanylyl cyclase | Activation | Stone and Marletta (1994) |
| Hemoglobin | Inhibition | Forster (1970) |
| Neuroglobin | Inhibition | Burmester et al. (2000) |
| Myoglobin | Inhibition | Coburn and Mayers (1971) |
| Cytoglobin | Inhibition | Geuens et al. (2003); Sawai et al. (2003) |
| NADPH oxidase | Inhibition | Taille et al. (2004) |
| NO synthases | Inhibition | Willis et al. (1995); Thorup et al. (1999) |
| Peroxidases | Binding | Carlsson et al. (2005) |
| Prostaglandin H synthase | Binding | Lou et al. (2000) |
| Tryptophan dioxygenase | Inhibition | Piantadosi (2002) |
| NPAS2 | Inhibition | Dioum et al. (2002) |