Useful databases for cell-based pharmacogenetics
| Database | URL | Description |
|---|---|---|
| HapMap | http://www.ncbi.nlm.nih.gov/geo/ | Basal expression data for HapMap samples using various microarray expression platforms |
| http://www.hapmap.org/ | Genetic variation data of >4 million SNPs | |
| PharmGKB | http://www.pharmgkb.org/ | Genotype and drug phenotype data for >600 genes, 500 drugs, and 500 diseases |
| NCI60 | https://dtp.nci.nih.gov/ | SNP, expression, and CNV data on 59 cell lines from various tissues, as well as cytotoxicity data for over 40,000 compounds |
| http://discover.nci.nih.gov/ | Free bioinformatics and data mining tools for use with the genetic and drug phenotype data | |
| SCANdb | http://www.SCANdb.org | Results of genomewide association studies between basal expression of over 13,000 transcripts and genotypes of hundreds of thousands of SNPs in the HapMap CEU and YRI samples |
| Cancer Genome Project | http://www.sanger.ac.uk/genetics/CGP/ | Collection of somatically acquired mutations and other sequence variants in genes that drive oncogenesis |
| VIP Genes and 1000 Genomes | http://genemed1.bsd.uchicago.edu/pharmacodb/thougen/main.php | Organizes the results of high-coverage, deep resequencing of 39 VIP genes in four subjects from the 1000 Genomes project, as well as lower coverage resequencing of 57 other subjects |