Examples of inflammatory mediators important in the pathogenesis of LPS-induced liver injury
| Mediator | Reference Demonstrating Contribution to Liver Injury |
|---|---|
| TNF | Hewett et al., 1993 |
| PMN chemokines | Li et al., 2004 |
| PMNs | Hewett et al., 1992; Ishii et al., 2002; Gujral et al., 2004 |
| Platelets | Pearson et al., 1996a |
| Thrombin | Hewett and Roth, 1995; Moulin et al., 2001 |
| Kupffer cells | Vollmar et al., 1996; Brown et al., 1997 |