TABLE 2

Differential regulation of ghrelin gene products on gastroduodenal motility in freely moving conscious rats

Drugs	Drug Administration	Status	MI		Frequency of Phase III-Like Contractions
Drugs	Drug Administration	Status	Antrum	Duodenum	Antrum	Duodenum
Rat acyl ghrelin	i.v. and i.c.v.	Acutely fed	↑	↑		↑
		Fasted	N.A.	N.A.	↑	↑
Rat des-acyl ghrelin	i.v. and i.c.v.	Acutely fed			N.A.	N.A.
		Fasted	N.A.	N.A.	↓
Rat obestatin	i.v.	Acutely fed	↓		↓	↓
		Fasted	N.A.	N.A.

i.c.v., intracerebroventricular; i.v., intravenous; MI, motility index; N.A., not applicable.