TABLE 1

Human uptake and efflux transporter gene, mRNA, and protein nomenclature

The gene names and the chromosomal locations were obtained from Entrez Gene cytogenic band. The mRNA and splice variant information were obtained from NCBI Entrez Nucleotide. Protein names (including alternative names) were obtained from UniProt/Swiss-Prot and GeneCards.

GenemRNAProtein
NameLocusAccession NoSplice VariantsNameOther Names
SLC Transporters
    SLCO1A212p12NM_021094YesOATP1A2OATP, OATP-A
    SLCO1B112p12NM_006446OATP1B1OATP2, LST-1, OATP-C
    SLCO1B312p12NM_019844OATP1B3OATP8, LST-2
    SLCO1C112p12NM_001145946YesOATP1C1OATP-F
    SLCO2A13q21NM_005630YesOATP2A1PGT
    SLCO2B111q13NM_007256YesOATP2B1OATP-B
    SLCO3A115q26NM_013272YesOATP3A1OATP-D
    SLCO4A120q13NM_016354YesOATP4A1OATP-E
    SLCO4C15q21NM_180991OATP4C1OATP-H
    SLCO5A18q13NM_030958YesOATP5A1OATP-J
    SLCO6A15q21NM_173488OATP6A1OATP-I, GST
    SLC22A16q26NM_003057YesOCT1
    SLC22A26q26NM_003058YesOCT2
    SLC22A36q26–27NM_021977OCT3EMT, Orct3
    SLC22A45q31.1NM_003059OCTN1ET
    SLC22A55q31NM_003060OCTN2
    SLC22A215q31N.D.OCTN3
    SLC22A611q13.1–2NM_004790YesOAT1NKT
    SLC22A76q21.1–2NM_153320YesOAT2NLT
    SLC22A811q11NM_004254YesOAT3Roct
    SLC22A1111q13.1NM_018484YesOAT4
    SLC22A10/1911q12.3NM_001039752OAT5
    SLC22A2011q13.1NM_001004326YesOAT6
    SLC22A911q13.1NM_080866OAT7hUST3
    SLC22A1211q13.1NM_144585YesURATRST
    SLC10A114q24.1NM_003049NTCP
    SLC10A213q33NM_000452ASBTIBAT, ISBT
    SLC15A113q33-q34NM_005073YesPEPT1HPEPT1
    SLC15A23q13.33NM_021082YesPEPT2
    SLC28A115q25-q26NM_004213YesCNT1hCNT1
    SLC28A215q15NM_004212CNT2SPNT, hCNT2
    SLC28A39q22.2NM_001532CNT3hCNT3
    SLC29A16p21.2-p21.1NM_001078177YesENT1
    SLC29A211q13NM_022127YesENT2DER12, HNP36
    SLC29A310q22.1NM_018344YesENT3
    SLC47A117p11.2NM_018242YesMATE1
    SLC47A217p11.2NM_152908YesMATE2-KH+/cation antiporter
ABC Transporters
    ABCA19q31.1NM_005502ABCA1
    ABCB17q21.1NM_000927MDR1Pgp
    ABCB47q21.1NM_000443YesMDR3PFIC3, PGY3
    ABCB112q24NM_003742BSEPSPGP, PFIC2
    ABCC116p13.1NM_004996YesMRP1MRP, GS-X
    ABCC210q24NM_000392MRP2cMOAT, DJS
    ABCC317q22NM_003786YesMRP3MOAT-D, cMOAT2
    ABCC413q32NM_005845YesMRP4MOAT-B
    ABCC53q27NM_005688YesMRP5MOAT-C, ABC11
    ABCC616p13.1NM_001171YesMRP6MOAT-E, PXE, ARA
    ABCC106p21.1NM_033450YesMRP7
    ABCC1116q12.1NM_032583YesMRP8
    ABCC1216q12.1NM_033226YesMRP9
    ABCG24q22NM_004827YesBCRPMXR
    ABCG52p21NM_022436ABCG5Sterolin-1
    ABCG82p21NM_022437ABCG8Sterolin-2
    ATP7B13q14.3NM_000053YesATP7BWD
    ATP8B118q21-q22NM_005603ATP8B1PFIC1, FIC1, BRIC
    OSTα3q29NM_152672OSTα
    OSTβ15q22.31NM_178859OSTβ
  • ET, ergothioneine transporter; NKT, novel kidney transporter; NLT, novel liver transporter; Roct, reduced in osteosclerosis transporter; IBAT/ISBT, ileal sodium-dependent bile acid cotransporter; RST, renal-specific transporter; SPNT, sodium-dependent purine nucleoside transporter.