Cellular Localization | Tissue | Species | Cell Types | References |
---|---|---|---|---|
Oct1 | ||||
Basolateral | Liver | R | Hepatocytes (centrilobular) | Meyer-Wentrup et al., 1998 |
Basolateral | Kidney | R | Proximal tubule cells (S1/S2) | Karbach et al., 2000 |
Basolateral | Jejunum | H | Enterocytes | Muller et al., 2005 |
Basolateral | Testes | R | Sertoli cells | Maeda et al., 2007a |
Apical | Lung | R, H | Ciliated epithelial cells | Lips et al., 2005 |
Oct2 | ||||
Basolateral | Kidney | R, H | Proximal tubule cells (S2/S3) | Karbach et al., 2000; Motohashi et al., 2002 |
Apical | Lung | R, H | Ciliated epithelial cells | Lips et al., 2005 |
Apical | Choroid plexus | R | Epithelial cells | Sweet et al., 2001 |
Apical | Olfactory mucosa | B | Epithelial cells | Chemuturi and Donovan, 2007 |
Oct3 | ||||
Basolateral | Kidney | H | Proximal tubule cell line | Glube and Langguth, 2008 |
Basolateral | Placenta | H | Syncytiotrophoblasts | Sata et al., 2005 |
Apical | Jejunum | H | Enterocytes | Muller et al., 2005 |
Apical | Testes | R | Sertoli cells | Maeda et al., 2007a |
Apical | Lung | R, H | Ciliated epithelial cells | Lips et al., 2005 |
Octn1 | ||||
Apical | Kidney | M | Proximal tubule cells | Tamai et al., 2004 |
Apical | Eye | H | Corneal-limbal and conjunctival epithelium | Garrett et al., 2008 |
N.D. | Heart | M | Endothelial cells in blood vessels | Iwata et al., 2008 |
Octn2 | ||||
Apical | Kidney | M, R, H | Proximal tubule cells | Tamai et al., 2001a; Masuda et al., 2006 |
Apical | Placenta | H | Syncytiotrophoblasts | Lahjouji et al., 2004; Grube et al., 2005 |
Apical | Small intestine | R | Enterocytes | Duran et al., 2005 |
Apical | Eye | H | Corneal-limbal and conjunctival epithelium | Garrett et al., 2008 |
Apical | Epididymis | M | Principal cells, spermatozoa | Yakushiji et al., 2006; Kobayashi et al., 2007 |
Basolateral | Epididymis | R | Epithelia of distal caput and corpus | Rodriguez et al., 2002 |
Basolateral | Testes | R | Sertoli cells | Kobayashi et al., 2005a |
Basolateral | Brain | R | Capillary endothelial cells | Miecz et al., 2008 |
N.D. | Brain | M, R | Olfactory bulb and nerve, cortex, cerebellum, spinal cord, hippocampus, hypothalamus, choroid plexus, astrocytes | Inazu et al., 2006; Lamhonwah et al., 2008 |
N.D. | Pancreas | M | α Cells | Kai et al., 2005 |
N.D. | Heart | M, H | Cardiac muscle cells, endothelial cells | Grube et al., 2006b; Iwata et al., 2008 |
Octn3 | ||||
Basolateral | Small intestine | R | Enterocytes | Duran et al., 2005 |
N.D. | Epididymis | M | Spermatozoa | Kobayashi et al., 2007 |
N.D. | Brain | M | Olfactory bulb and nerve, cortex, cerebellum, grey matter, hippocampus, hypothalamus, choroid plexus | Lamhonwah et al., 2008 |
Oat1 | ||||
Basolateral | Kidney | M, R, H | Proximal tubule cells | Hosoyamada et al., 1999; Tojo et al., 1999; Eraly et al., 2006 |
Basolateral | Choroid plexus | M | Ependymal cells | Bahn et al., 2005 |
N.D. | Muscle | H | Skeletal muscle cells | Takeda et al., 2004 |
N.D. | Adrenal gland | R | Outer zona fasciculate | Beery et al., 2003 |
Oat2 | ||||
Basolateral | Liver | R | Hepatocytes | Simonson et al., 1994 |
Basolateral | Kidney | H | Proximal tubule cells | Enomoto et al., 2002b |
Apical | Kidney | M, R | Proximal tubule cells | Kojima et al., 2002; Ljubojevic et al., 2007 |
Oat3 | ||||
Basolateral | Kidney | M, R, H | Proximal tubule cells | Cha et al., 2001; Kojima et al., 2002; Bahn et al., 2005 |
Basolateral | Eye | R | Retinal vascular endothelial cells | Hosoya et al., 2008 |
Basolateral | Brain | R | Capillary endothelial cells | Kikuchi et al., 2003; Roberts et al., 2008 |
Apical | Choroid plexus | M | Epithelial cells | Sweet et al., 2002; Sykes et al., 2004 |
N.D. | Muscle | H | Skeletal muscle cells | Takeda et al., 2004 |
Oat4 | ||||
Apical | Kidney | H | Proximal tubule cells | Babu et al., 2002a; Ekaratanawong et al., 2004 |
Basolateral | Placenta | H | Syncytiotrophoblasts | Ugele et al., 2008 |
Oat5 | ||||
Apical | Kidney | R | Proximal tubule cells | Anzai et al., 2005 |
Oat6 | ||||
N.D. | Olfactory mucosa | M | Olfactory cells | Monte et al., 2004 |
Oat7 | ||||
Basolateral | Liver | H | Hepatocytes | Shin et al., 2007 |
Urat1 | ||||
Apical | Kidney | M, H | Proximal tubule cells | Enomoto et al., 2002a; Hosoyamada et al., 2004 |
N.D., not determined.