Species, Dose, Duration, Regimen, Brain Region | Subunit Polypeptide | Reference | |||||
---|---|---|---|---|---|---|---|
β1 | β2 | β3 | γ1 | γ2 | δ | ||
% change | |||||||
Rat, 5g/kg/d, 6 d | Mhatre and Ticku, 1994 | ||||||
Intragastric intubation | |||||||
Cerebral cortex | +23 | +23 | |||||
Rat, 10–12 g/kg/d, 14 d | Devaud et al., 1997 | ||||||
Forced ethanol administration | |||||||
Cerebral cortex | +36 | +36 | +30 | N.S. | |||
Rat, 10 g/kg/d, 14 d | Matthews et al., 1998 | ||||||
Forced ethanol administration | |||||||
Hippocampus | N.S. | N.S. | N.S. | ||||
Rat, 10 g/kg/d, 40 d | Matthews et al., 1998 | ||||||
Forced ethanol administration | |||||||
Cerebral cortex | N.S. | N.S. | N.S. | ||||
Hippocampus | N.S. | N.S. | N.S. | ||||
Rat, 9 g/kg/d, 6 d | Marutha Ravindran et al., 2007a | ||||||
Intragastric intubation | |||||||
Cerebral cortex | +34 | N.S. | |||||
Cerebellum | +31 | N.S. | |||||
Hippocampus | N.S. | +32 | |||||
Rat, 9 g/kg/d, 6 d | Marutha Ravindran et al., 2007b | ||||||
Intragastric intubation | |||||||
Cerebral cortex | N.S. | ||||||
Cerebellum | −35 | ||||||
Hippocampus | −25 |
d, day(s); N.S., not significantly different from the control value.