Cumulative risk of myopathy associated with SLCO1B1 rs4149056 genotypes and simvastatin at 80 mg daily dose
Data from SEARCH Collaborative Group, 2008.
| Genotype | Population Frequency | Myopathy Odds Ratio | Year 1 | Year 5 | ||
|---|---|---|---|---|---|---|
| Total | Proportion Attributable to Genotype | Total | Proportion Attributable to Genotype | |||
| % | % | |||||
| TT | 0.730 | 1.0 | 0.34 | 0 | 0.63 | 0 |
| CT | 0.249 | 4.5 | 1.38 | 75 | 2.83 | 78 |
| CC | 0.021 | 16.9 | 15.25 | 98 | 18.55 | 97 |
| All | 1.000 | 28.40 | 63 | 1.56 | 60 | |