TABLE 2

Tissues highly enriched with NHERF family members

NHERFTissue
NHERF 1Kidney (proximal tubules), gastrointestinal tract (small intestine, colon, and gastric parietal cells), airway epithelium, liver, mesothelium, breast, placenta, brain
NHERF 2Kidney (glomeruli, peritubular capillaries, collecting duct principal cells and weakly in proximal tubules), gastrointestinal tract (small intestine and colon), lung, colon cancer, brain
NHERF 3Kidney, gastrointestinal tract, liver
NHERF 4Kidney, gastrointestinal tract