Subcellular distribution of NHERF proteins
| Location | |
|---|---|
| NHERF 1 | Brush-border and basolateral membranes (slight) |
| Actin-rich structures including membrane ruffles, microvilli, and filopodia | |
| Cell surface structures with ERM proteins | |
| Apical regions in the membrane | |
| NHERF 2 | Brush-border membranes |
| Cell surface structures with ERM proteins | |
| Apical and subapical regions and cytosol | |
| NHERF 3 | Brush-border membranes |
| Apical and subapical structures | |
| NHERF 4 | Subapical regions and cytosol |