TABLE 9

Conantokins inhibiting NMDA glutamate receptors

Species	Diet	Name	Sequence	NMDA Selectivity	References
C. caracteristicus	V	Con-Ca2	GYγγRγIAγTVRγLEEA	N.D.	Franco et al., 2006
C. ermineus	P	Con-E	GEγγHSKYQγCLRγIRVNNVQQγC	N.D.	Gowd et al., 2008
C. geographus	P	Con-G	GEγγLQγNQγLIRγKSN^*	NR2B > NR2C, NR2D	McIntosh et al., 1984; Gowd et al., 2008
C. gloriamaris	M	Con-Gm	GAKγRNNAγAVRγRLEEI	N.D.	Franco et al., 2006
C. lynceus	V	Con-L	GEγγVAKMAAγLARγDAVN^*	N.D.	Jimenez et al., 2002
C. purpurascens	P	Con-P	GEγγHSKYQγCLRγIRVNKVQQγC	NR2B, NR2A	Gowd et al., 2008
C. orchroleucus	V	Con-Oc	GEγγRKAMAγLEAKKAQγALKA	N.D.	Franco et al., 2006
C. parius	P	Con-Pr1	GEDγYAγGIRγYQLIHGKI	NR2B, NR2D	Teichert et al., 2007b
		Con-Pr2	DEPγYAγAIRγYQLKYGKI	NR2B > NR2D	Teichert et al., 2007b
		Con-Pr3	GEPγVAKWAγGLRγKAASN^*	NR2B, NR2D	Teichert et al., 2007b
C. quercinus	V	Con-Qu	GYγγRγVAγTVRγLDAA	N.D.	Franco et al., 2006
C. radiatus	P	Con-R	GEγγVAKMAAγLARγNIAKGCKVNCYP	NR2B, NR2A	White et al., 2000
C. sulcatus (brettinghami)	P	Con-Br	GDγγYSKFIγRERγAGRLDLSKFP	NR2B, NR2D, NR2A > NR2C	Twede et al., 2009
C. tulipa	P	Con-T	GEγγYQKMLγNLRγAEVKKNA^*	NR2B, NR2A	Haack et al., 1990; Klein et al., 2001